Why did we get into a Civil War?

Though slavery, and state's rights through the desire to maintain slavery, is the major cause of the Civil War it is not something that happened overnight.  Like any conflict there is always a build up.  There were many compromises that held the union together, but in any compromise there are losers and winners.  Furthermore, every moral issue faces the reality of economics and culture that often lead to delay.  Would the industrial revolution have pushed slavery aside?  Why didn't the South simply transition to a waged-based labor system?  Was our nation destined to be the agrarian culture Jefferson longed for or would Hamilton's business-focused economy win?  Sometimes force is the only answer no matter how devastating.